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Oladapo Bakare

Professor of Chemistry

Mailing Address:
Howard University
Department of Chemistry
525 College St., NW
Washington DC , 20059
Phone: (202)-806-6888

B.Sc. Chemistry, University of Ibadan, Nigeria
M.Sc. Chemistry (Analytical), University of Ibadan, Nigeria
Ph.D. Chemistry (Organic), The University of Hong Kong, Hong Kong
Post-Doctoral Fellow, Georgia Institute of Technology, Atlanta GA, USA

Research Interests

Design and synthesis of small organic molecule inhibitors/modulators of biochemical pathways involved in cancer development and  cancer cell survival.

Recent Publications

1. Bakare, O.; Ashendel, C. L.; Peng, H.; Zalkow L.H.; Burgess, E.M. Synthesis and MEK1 inhibitory Activities of Imido- Substituted 2-Chloro-1,4-naphthoquinones. Bioorg. Med. Chem. 2003, 11, 3165-3170.

2. Anderson, A.J.; Nicholson, J.M.; Bakare, O.; Butcher, R.J.; Scott, K.R. A Base-Catalyzed Solution Phase Parallel Synthesis of Substituted Vinylic Benzamides from 3-Amino-2-cyclohexanones. J. Comb. Chem. 2004, 6, 950-954.

3. Pan, G.; Lemmouchi, Y.; Akala, E. O.; Bakare, O. Studies on PEGylated and Drug-Loaded PAMAM Dendrimers. Journal of Bioactive and Compatible Polymers. 2005, 20, 113-128.

4. Bakare, O.; John, N.; Butcher, R. J. Zalkow, L. H. 12-Methoxy-15-(4-morpholino)podocarpa-8,11,13-trien-15-one. Acta Cryst. E. 2005, o3791-o3793

5. Anderson, A. J.; Nicholson, J. M.; Bakare, O.; Butcher, R. J.; Wilson, T. L.; Scott, K. R. Enaminones 9.Further studies on the anticonvulsant activity and potential type IV phosphodiesterase inhibitory activity of substituted vinylic benzamides. Bioorg. Med.Chem. 2006, 14, 997-1006.

6. Qiao, Z.; Udeochu, U.; Jimerson, T.; Fletcher, M.; Bakare, O.; Hosten, C. M. Detection of Benzopyrene-deoxyguanosine adducts by matrix assisted laser desorption/ ionization time of flight mass spectrometry (MALDI –TOFMS). Rapid Commun. Mass Spectrom. 2006, 20, 487-492.

7. Butcher, R. J.; Bakare, O.; John, N. J. 12-Methoxy-15-(1-pyrrolidino)podocarpa-8,11,13-trien-15-one. Acta Cryst. E62. 2006, o945-o947

8. John, N. J.; Butcher, R. J.; Bakare, O. 15-(4-chlorobenzylamino)-12- Methoxypodocarpa-8,11, 13-trien-15-one. Acta Cryst. E62. 2006, o4361-o4363

9. Udeochu, U.; Jimerson, T.; Vivoni, A.; Bakare, O.; Hosten, C. M. Vibrational assignment of the raman active modes of 1,10-phenanthroline-5,6-dione using DFT calculations. J. Phys. Chem. A. 2007, 111(17), 3409-3415.

10. Copeland, R. L. Jr.; Das, J.R.; Bakare, O.; Enwerem, N.M.; Berhe, S.; Hillaire, K.; White, D.; Beyene, D.; Kassim, K.; Kanaan, Y.; Cytotoxicity of 2,3-dichloro-5,8- dimethoxy-1,4-naphthoquinone in androgen-dependent and –independent prostate cancer cell lines. Anticancer Research. Anticancer Research. 2007, 27, 1537-1546.

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